{"id":620,"date":"2024-11-04T11:07:55","date_gmt":"2024-11-04T02:07:55","guid":{"rendered":"https:\/\/wako-psy-clinic.com\/kimoto\/?p=620"},"modified":"2024-11-04T11:07:55","modified_gmt":"2024-11-04T02:07:55","slug":"adhd%e3%81%ab%e5%af%be%e3%81%97%e3%81%a6%e6%97%a5%e6%9c%ac%e3%81%a7%e4%bd%bf%e7%94%a8%e5%8f%af%e8%83%bd%e3%81%aa%e5%86%85%e6%9c%8d%e3%81%99%e3%81%b9%e3%81%a6%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"post","link":"https:\/\/wako-psy-clinic.com\/kimoto\/blog\/620.html","title":{"rendered":"ADHD\u306b\u5bfe\u3057\u3066\u65e5\u672c\u3067\u4f7f\u7528\u53ef\u80fd\u306a\u5185\u670d\u3059\u3079\u3066\u306b\u3064\u3044\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n
ADHD\u306b\u5bfe\u3057\u3066\u65e5\u672c\u3067\u4f7f\u7528\u53ef\u80fd\u306a\u5185\u670d\u3059\u3079\u3066\u306b\u3064\u3044\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066

\u4eca\u56de\u306f\u3001ADHD\u306b\u5bfe\u3057\u3066\u65e5\u672c\u3067\u4f7f\u7528\u53ef\u80fd\u306a\u5185\u670d\u3059\u3079\u3066\u306b\u3064\u3044\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002

ADHD\uff08\u6ce8\u610f\u6b20\u9665\u30fb\u591a\u52d5\u6027\u969c\u5bb3\uff09\u306e\u6cbb\u7642\u306b\u306f\u3001\u85ac\u7269\u7642\u6cd5\u304c\u52b9\u679c\u7684\u306a\u65b9\u6cd5\u306e\u4e00\u3064\u3067\u3059\u3002\u65e5\u672c\u3067\u4f7f\u7528\u53ef\u80fd\u306aADHD\u6cbb\u7642\u85ac\u306b\u306f\u3001\u4e3b\u306b\u4e2d\u67a2\u795e\u7d4c\u523a\u6fc0\u85ac\u3068\u975e\u523a\u6fc0\u85ac\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u3084\u7279\u5fb4\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u3001\u65e5\u672c\u3067\u627f\u8a8d\u3055\u308c\u3066\u3044\u308b\u4e3b\u8981\u306aADHD\u6cbb\u7642\u85ac\u306e\u7279\u5fb4\u3092\u8aac\u660e\u3057\u307e\u3059\u3002

1. \u30e1\u30c1\u30eb\u30d5\u30a7\u30cb\u30c7\u30fc\u30c8\u5869\u9178\u5869\uff08\u5546\u54c1\u540d\uff1a\u30b3\u30f3\u30b5\u30fc\u30bf\uff09
\u5206\u985e: \u4e2d\u67a2\u795e\u7d4c\u523a\u6fc0\u85ac
\u4f5c\u7528\u6a5f\u5e8f: \u30e1\u30c1\u30eb\u30d5\u30a7\u30cb\u30c7\u30fc\u30c8\u306f\u3001\u8133\u5185\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u3068\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u518d\u53d6\u308a\u8fbc\u307f\u3092\u963b\u5bb3\u3057\u3001\u3053\u308c\u3089\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u6fc3\u5ea6\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6ce8\u610f\u529b\u3084\u96c6\u4e2d\u529b\u304c\u5411\u4e0a\u3057\u3001\u885d\u52d5\u6027\u3084\u591a\u52d5\u6027\u304c\u6291\u5236\u3055\u308c\u307e\u3059\u3002

\u7279\u5fb4:
\u4e00\u65e5\u4e00\u56de\u306e\u670d\u7528\u3067\u52b9\u679c\u304c\u9577\u6642\u9593\u6301\u7d9a\uff088\u301c12\u6642\u9593\uff09
\u5c0f\u5150\u304b\u3089\u6210\u4eba\u307e\u3067\u5e45\u5e83\u3044\u5e74\u9f62\u5c64\u306b\u4f7f\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u6bd4\u8f03\u7684\u901f\u52b9\u6027\u304c\u3042\u308b
\u52b9\u679c\u304c\u6301\u7d9a\u3059\u308b\u305f\u3081\u3001\u5b66\u6821\u3084\u4ed5\u4e8b\u306e\u4e00\u65e5\u306e\u6d3b\u52d5\u3092\u30b5\u30dd\u30fc\u30c8\u3067\u304d\u308b

\u526f\u4f5c\u7528: \u98df\u6b32\u6e1b\u9000\u3001\u7761\u7720\u969c\u5bb3\u3001\u795e\u7d4c\u904e\u654f\u3001\u5fc3\u62cd\u6570\u3084\u8840\u5727\u306e\u4e0a\u6607\u306a\u3069

\u6ce8\u610f\u70b9: \u30b3\u30f3\u30b5\u30fc\u30bf\u306f\u4f9d\u5b58\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u51e6\u65b9\u306f\u53b3\u3057\u304f\u7ba1\u7406\u3055\u308c\u3066\u3044\u307e\u3059\u3002

2. \u30a2\u30c8\u30e2\u30ad\u30bb\u30c1\u30f3\uff08\u5546\u54c1\u540d\uff1a\u30b9\u30c8\u30e9\u30c6\u30e9\uff09
\u5206\u985e: \u975e\u523a\u6fc0\u85ac
\u4f5c\u7528\u6a5f\u5e8f: \u30a2\u30c8\u30e2\u30ad\u30bb\u30c1\u30f3\u306f\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u518d\u53d6\u308a\u8fbc\u307f\u3092\u9078\u629e\u7684\u306b\u963b\u5bb3\u3057\u3001\u8133\u5185\u306e\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u6fc3\u5ea6\u3092\u9ad8\u3081\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6ce8\u610f\u529b\u306e\u6539\u5584\u3084\u885d\u52d5\u6027\u306e\u6291\u5236\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002

\u7279\u5fb4:
\u4e00\u65e5\u4e00\u56de\u3001\u307e\u305f\u306f\u4e8c\u56de\u306e\u670d\u7528
\u4e2d\u67a2\u795e\u7d4c\u523a\u6fc0\u85ac\u3068\u306f\u7570\u306a\u308a\u3001\u4f9d\u5b58\u6027\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u3044
\u52b9\u679c\u304c\u73fe\u308c\u308b\u307e\u3067\u6570\u9031\u9593\u304b\u304b\u308b\u5834\u5408\u304c\u3042\u308b\uff08\u901f\u52b9\u6027\u3067\u306f\u306a\u3044\uff09
\u6210\u4eba\u306eADHD\u306b\u3082\u52b9\u679c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u308b

\u526f\u4f5c\u7528: \u5410\u304d\u6c17\u3001\u98df\u6b32\u6e1b\u9000\u3001\u7720\u6c17\u3001\u982d\u75db\u3001\u3081\u307e\u3044\u306a\u3069

\u6ce8\u610f\u70b9: \u52b9\u679c\u304c\u5b89\u5b9a\u3059\u308b\u307e\u3067\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u305f\u3081\u3001\u5373\u52b9\u6027\u3092\u6c42\u3081\u308b\u60a3\u8005\u306b\u306f\u4e0d\u5411\u304d\u306a\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002

3. \u30b0\u30a2\u30f3\u30d5\u30a1\u30b7\u30f3\uff08\u5546\u54c1\u540d\uff1a\u30a4\u30f3\u30c1\u30e5\u30cb\u30d6\uff09
\u5206\u985e: \u975e\u523a\u6fc0\u85ac
\u4f5c\u7528\u6a5f\u5e8f: \u30b0\u30a2\u30f3\u30d5\u30a1\u30b7\u30f3\u306f\u3001\u8133\u5185\u306e\u03b12A\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\u306b\u4f5c\u7528\u3057\u3001\u795e\u7d4c\u6d3b\u52d5\u3092\u8abf\u6574\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u885d\u52d5\u6027\u3084\u591a\u52d5\u6027\u3092\u6291\u5236\u3057\u3001\u6ce8\u610f\u529b\u3092\u6539\u5584\u3057\u307e\u3059\u3002

\u7279\u5fb4:
\u4e00\u65e5\u4e00\u56de\u306e\u670d\u7528
\u4e3b\u306b\u885d\u52d5\u6027\u3084\u591a\u52d5\u6027\u306e\u6539\u5584\u306b\u52b9\u679c\u304c\u3042\u308b
\u4f9d\u5b58\u6027\u304c\u4f4e\u304f\u3001\u5b89\u5168\u6027\u304c\u9ad8\u3044
\u9577\u6642\u9593\u52b9\u679c\u304c\u6301\u7d9a\u3057\u3001\u3086\u3063\u304f\u308a\u3068\u4f5c\u7528\u3059\u308b\u305f\u3081\u3001\u523a\u6fc0\u6027\u306e\u306a\u3044\u7a4f\u3084\u304b\u306a\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059

\u526f\u4f5c\u7528: \u7720\u6c17\u3001\u4f4e\u8840\u5727\u3001\u75b2\u52b4\u611f\u3001\u3081\u307e\u3044\u306a\u3069

\u6ce8\u610f\u70b9: \u8840\u5727\u3092\u4e0b\u3052\u308b\u52b9\u679c\u304c\u3042\u308b\u305f\u3081\u3001\u4f4e\u8840\u5727\u306e\u4eba\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u52b9\u679c\u304c\u73fe\u308c\u308b\u307e\u3067\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002

4. \u30ea\u30b9\u30c7\u30ad\u30b5\u30f3\u30d5\u30a7\u30bf\u30df\u30f3\u30e1\u30b7\u30eb\u9178\u5869\uff08\u5546\u54c1\u540d\uff1a\u30d3\u30d0\u30f3\u30bb\uff09
\u5206\u985e: \u4e2d\u67a2\u795e\u7d4c\u523a\u6fc0\u85ac
\u4f5c\u7528\u6a5f\u5e8f: \u30ea\u30b9\u30c7\u30ad\u30b5\u30f3\u30d5\u30a7\u30bf\u30df\u30f3\u306f\u3001\u4f53\u5185\u3067\u30c7\u30ad\u30b9\u30c8\u30ed\u30a2\u30f3\u30d5\u30a7\u30bf\u30df\u30f3\u306b\u5909\u63db\u3055\u308c\u3001\u8133\u5185\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u3068\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u6fc3\u5ea6\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6ce8\u610f\u529b\u3084\u96c6\u4e2d\u529b\u304c\u5411\u4e0a\u3057\u3001\u885d\u52d5\u6027\u3084\u591a\u52d5\u6027\u304c\u6291\u5236\u3055\u308c\u307e\u3059\u3002

\u7279\u5fb4:
\u4e00\u65e5\u4e00\u56de\u306e\u670d\u7528\u3067\u52b9\u679c\u304c12\u6642\u9593\u7a0b\u5ea6\u6301\u7d9a
\u98df\u6b32\u6291\u5236\u306e\u4f5c\u7528\u304c\u3042\u308b\u305f\u3081\u3001ADHD\u306e\u6cbb\u7642\u306b\u52a0\u3048\u3001\u904e\u98df\u306b\u60a9\u3080\u60a3\u8005\u306b\u3082\u6709\u7528\u306a\u3053\u3068\u304c\u3042\u308a\u307e\u3059
\u4f9d\u5b58\u6027\u306e\u30ea\u30b9\u30af\u304c\u3042\u308b\u305f\u3081\u3001\u53b3\u3057\u3044\u7ba1\u7406\u306e\u3082\u3068\u51e6\u65b9\u3055\u308c\u307e\u3059

\u526f\u4f5c\u7528: \u98df\u6b32\u6e1b\u9000\u3001\u7761\u7720\u969c\u5bb3\u3001\u53e3\u6e07\u3001\u5fc3\u62cd\u6570\u3084\u8840\u5727\u306e\u4e0a\u6607\u3001\u795e\u7d4c\u904e\u654f\u306a\u3069

\u6ce8\u610f\u70b9: \u4f9d\u5b58\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u9069\u5207\u306a\u76e3\u8996\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u98df\u6b32\u6291\u5236\u304c\u5f37\u3044\u305f\u3081\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002

\u307e\u3068\u3081
\u65e5\u672c\u3067\u4f7f\u7528\u53ef\u80fd\u306aADHD\u306e\u6cbb\u7642\u85ac\u306b\u306f\u3001\u4e3b\u306b\u4e2d\u67a2\u795e\u7d4c\u523a\u6fc0\u85ac\u3068\u975e\u523a\u6fc0\u85ac\u306e2\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u305e\u308c\u306e\u85ac\u306f\u3001\u4f5c\u7528\u6a5f\u5e8f\u3084\u52b9\u679c\u306e\u73fe\u308c\u65b9\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u60a3\u8005\u306e\u75c7\u72b6\u3084\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3001\u6cbb\u7642\u76ee\u7684\u306b\u5408\u308f\u305b\u3066\u9078\u629e\u3055\u308c\u307e\u3059\u3002

\u901f\u52b9\u6027\u3092\u6c42\u3081\u308b\u5834\u5408: \u4e2d\u67a2\u795e\u7d4c\u523a\u6fc0\u85ac\u3067\u3042\u308b\u30b3\u30f3\u30b5\u30fc\u30bf\u3084\u30d3\u30d0\u30f3\u30bb\u304c\u52b9\u679c\u7684\u3067\u3059\u3002\u7279\u306b\u3001\u5373\u52b9\u6027\u304c\u6c42\u3081\u3089\u308c\u308b\u5b66\u6821\u3084\u4ed5\u4e8b\u5834\u3067\u306e\u6ce8\u610f\u529b\u5411\u4e0a\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002
\u4f9d\u5b58\u6027\u3092\u907f\u3051\u305f\u3044\u5834\u5408: \u975e\u523a\u6fc0\u85ac\u3067\u3042\u308b\u30b9\u30c8\u30e9\u30c6\u30e9\u3084\u30a4\u30f3\u30c1\u30e5\u30cb\u30d6\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u9577\u671f\u7684\u306a\u4f7f\u7528\u306b\u9069\u3057\u3066\u304a\u308a\u3001\u4f9d\u5b58\u6027\u306e\u30ea\u30b9\u30af\u304c\u5c11\u306a\u3044\u70b9\u304c\u7279\u5fb4\u3067\u3059\u3002
\u6cbb\u7642\u85ac\u306e\u9078\u629e\u306f\u3001\u533b\u5e2b\u3068\u76f8\u8ac7\u3057\u306a\u304c\u3089\u60a3\u8005\u4e00\u4eba\u3072\u3068\u308a\u306e\u30cb\u30fc\u30ba\u306b\u5408\u308f\u305b\u3066\u6c7a\u5b9a\u3055\u308c\u308b\u3079\u304d\u3067\u3059\u3002



Today, I\u2019ll explain the characteristics of all the available oral medications in Japan for treating ADHD (Attention Deficit Hyperactivity Disorder).

In Japan, ADHD treatment includes two primary categories of medications: central nervous system stimulants and non-stimulants. Each category has a unique mechanism of action and distinctive characteristics. Here is an overview of the main ADHD medications approved in Japan and their specific features.

1. Methylphenidate Hydrochloride (Concerta)
Type: Central Nervous System Stimulant

Mechanism: Methylphenidate blocks the reuptake of dopamine and norepinephrine in the brain, increasing their concentration. This enhances focus and attention while reducing impulsivity and hyperactivity.

Features:

Once-daily dosing with long-lasting effects (8\u201312 hours)
Suitable for a wide age range, including children and adults, with relatively fast-acting results
Ideal for supporting daily activities at school or work
Side Effects: Appetite suppression, insomnia, nervousness, increased heart rate, and blood pressure

Notes: Due to its potential for dependence, Concerta is strictly regulated and monitored.

2. Atomoxetine (Strattera)
Type: Non-stimulant

Mechanism: Atomoxetine selectively inhibits the reuptake of norepinephrine, increasing its concentration in the brain, which improves attention and reduces impulsivity.

Features:

Taken once or twice daily
Lower risk of dependence compared to stimulants
Effects may take several weeks to become noticeable
Side Effects: Nausea, appetite suppression, drowsiness, headache, and dizziness

Notes: Since Strattera requires time to reach full effect, it may not be suitable for patients needing immediate symptom relief.

3. Guanfacine (Intuniv)
Type: Non-stimulant

Mechanism: Guanfacine targets alpha-2A adrenergic receptors in the brain, modulating neural activity, which helps reduce impulsivity and hyperactivity while enhancing attention.

Features:

Once-daily dosing
Particularly effective for improving impulsivity and hyperactivity
Low dependency risk with a gradual, non-stimulant effect
Side Effects: Drowsiness, low blood pressure, fatigue, and dizziness

Notes: Those with low blood pressure should use it cautiously. Effects may take time to manifest.

4. Lisdexamfetamine Mesylate (Vyvanse)
Type: Central Nervous System Stimulant

Mechanism: Lisdexamfetamine converts to dextroamphetamine in the body, which then increases dopamine and norepinephrine levels in the brain, improving focus and reducing impulsivity and hyperactivity.

Features:

Once-daily dosing with effects lasting approximately 12 hours
Appetite-suppressing effects may benefit patients with coexisting overeating concerns
Strict regulation due to potential for dependence
Side Effects: Appetite suppression, insomnia, dry mouth, increased heart rate and blood pressure, nervousness

Notes: Close monitoring is required to manage potential dependency, and attention to weight loss due to appetite suppression is necessary.

Summary
In Japan, ADHD medications are broadly classified into two categories: stimulants and non-stimulants, each with unique mechanisms and benefits that suit different patient needs.

For rapid effect: Stimulants like Concerta and Vyvanse are effective for quick improvements, especially for attention demands at school or work.
To avoid dependency risks: Non-stimulants like Strattera and Intuniv are preferable. These are suited for long-term use with low dependency risk.
Choosing the right treatment should be a collaborative decision between the patient and physician, tailored to the patient\u2019s symptoms, lifestyle, and treatment goals.
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