{"id":919,"date":"2025-05-18T14:37:15","date_gmt":"2025-05-18T05:37:15","guid":{"rendered":"https:\/\/wako-psy-clinic.com\/kimoto\/?p=919"},"modified":"2025-05-18T14:37:15","modified_gmt":"2025-05-18T05:37:15","slug":"%e3%81%86%e3%81%a4%e7%97%85%e3%81%ae%e7%97%87%e7%8a%b6%e3%80%81%e8%84%b3%e6%a9%9f%e8%83%bd%e3%81%ab%e3%82%88%e3%82%8b%e7%97%87%e7%8a%b6%e3%81%a0%e3%81%91%e3%81%a7%e3%81%af%e3%81%aa%e3%81%84%e3%80%81","status":"publish","type":"post","link":"https:\/\/wako-psy-clinic.com\/kimoto\/blog\/919.html","title":{"rendered":"\u3046\u3064\u75c5\u306e\u75c7\u72b6\u3001\u8133\u6a5f\u80fd\u306b\u3088\u308b\u75c7\u72b6\u3060\u3051\u3067\u306f\u306a\u3044\u3001\u795e\u5948\u5ddd\u770c\u539a\u6728\u5e02\u306e\u5150\u7ae5\u7cbe\u795e\u79d1\u533b\u304c\u89e3\u8aac"},"content":{"rendered":"\n
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Today, I\u2019d like to discuss the idea that depressive symptoms are not caused solely by brain dysfunction.

When we think of depression, we often associate it with symptoms such as:

Loss of motivation

Depressed mood

Loss of interest

Decreased concentration

Memory difficulties

Anxiety

Insomnia

Fatigue

Autonomic nervous system disturbances

However, not all of these symptoms originate purely from a decline in brain function.

Take physical fatigue and autonomic symptoms, for example\u2014they are easier to recognize as not purely neurologically driven.

Yet most antidepressants target only serotonin or norepinephrine levels in the brain.

And realistically, depression is unlikely to be caused by a simple drop in just those specific neurotransmitters. Still, that is the extent of our current pharmacological options.

The human body has an innate ability to return to equilibrium\u2014even after temporary dysfunction or stress.
So in some cases, people may recover from depression without medication, simply through the passage of time.

Of course, antidepressants are approved after rigorous double-blind, placebo-controlled clinical trials.
And yes, these trials do show statistically significant efficacy.

However, it\u2019s also well known that placebos often have considerable effects in psychiatric research.

Depression is not a single, uniform illness.
Rather, it\u2019s a collection of symptoms that reflect dysfunctions throughout the body\u2014not just the brain.

In fact, it often appears as if the entire body\u2019s cells are simultaneously under stress or damage.

Some researchers suggest that chronic inflammation may be one underlying mechanism, and I think this is a useful framework.

Therefore, any treatment that promotes cellular repair or reduces systemic inflammation may potentially be effective.

For example, exosome therapy, which originates from regenerative medicine, has shown promising results\u2014perhaps for that very reason.

TMS (Transcranial Magnetic Stimulation) is also effective, as it stimulates brain activity.
However, it may have less pronounced effects on systemic (bodily) symptoms compared to mental ones.

That\u2019s why it\u2019s important that we don\u2019t focus solely on \u201cbrain function\u201d in the treatment of psychiatric disorders.
We need a broader view that treats depression as a whole-body condition.

This perspective applies to both children and adults alike.

Medication can certainly be a helpful option.
But if we cling only to that, it may not be enough to bring about full recovery.
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